#Signalling Mechanisms

[crimsonpublishersobesityjourna]

Can Gestational Anti-Diabetic Plants Using in Cameroon Manage Preeclampsia?

Preeclampsia is a persistent hypertensive gestational disease that might happen during pregnancy (antepartum), during delivery (intrapartum) or after childbirth (postpartum). It is clinically characterized by maternal high hypertension (>140/90mmHg systolic/diastolic blood pressure) and massive proteinuria (>300mg/24h). Severe cases are manifested by the development of comorbidities such as eclampsia, liver damage, edema and scattered vascular coagulation in mother and the complications in the fetus like fetal growth restriction, premature birth and fetal death. In Africa, the prevalence of eclampsia varies from 1/100 to 1/1700 pregnancies, and Cameroon it happens in 0.92/1 100 deliveries. Our objective was to determine among antidiabetic and gestational plants used in Cameroon those that can control preeclampsia. To achieve this objective three following engines of research were used in Google, Google Scholar and PubMed: “a given antidiabetic plant treated gestational women with preeclampsia “; “a single given antidiabetic plant treated three complications of preeclampsia” and “a given antidiabetic plant may regulate hypertension in women with preeclampsia. Twelve (12) plants were recorded and belong to 10 families and 12 genera. Six plants (Curcuma longa, Brassica oleracea, Moringa oleifera, Passiflora incarnata, Passiflora edulis and Passiflora foetida) intervene in direct treatment of preeclampsia and all the twelve were used in symptomatic treatment of preeclampsia. The most important plants are Brassica oleracea and Solanum melongena with 127 and 99 repetitions respectively. Strong recommendation of further studies for finding non-toxic doses is necessary for developing anti-preeclampsia future phytodrugs.

Read more about this article: https://crimsonpublishers.com/iod/fulltext/IOD.000626.php

Read more about this journal: https://crimsonpublishers.com/iod/

[lonleyhumanbeing]

[king-of-eclipse]

Listening to the mechanisms progression so far

First taste: They sound like they're having so much fun! Haha fun shanty!

Dabbling: Omg they have stories??

...

Now: Y'AI 'NG'NGAH, YOG-SOTHOTH H'EE-L'GEB F'AI THRODOG UAAAH

OGTHROD AI'F GEB'L-EE'H YOG-SOTHOTH 'NGAH'NG AI'Y ZHRO

(Im so normal about the bifrost incident. Originally I didn't like it. I very much like it now.)

[stained-glass-cicada]

I love the mechanisms, great music, very trans

The kindest thing they ever did was never release an isolated version of the "Tim Goes Mad" bit of GPTvsTMK because my mentally ill 17 year old ass would have never listened to anything else.

[jiaxxnscribbles]

i just remembered that i can in fact post Old Art so here is an album cover project from last semester

Details below!

This was the second project of my Illustration Intensive I class last semester, and we had to either design or redesign an album cover, so I chose The Mechanisms

During the project I took a 4-hour detour trying to translate the Red Signal chant into norse runes, aka I threw it through a translator and tried (emphasis on tried) via wikipedia to fix any Weirdness despite knowing next to nothing about runes so its probably. Incredibly wrong lol

[jonny-bee-meowrt]

death to the mechanisms red signal death to the mechanisms red signal death to the mechanisms red signal death to the mechanisms red signal death to the mechanisms red signal d

[beelzeballing]

hello mechsblr. i dont go here but. has this been done before?

[staircasecleric]

Do you ever just sit down, take a deep breath and have to face the fact that y'ai ng'ngah yog-sothoth h'ee-l'geb f'ai throdog uaaah ogthrod ai'f geb'l-ee'h yog-sothoth 'ngah'nh ai'yzhro

[hellafluff]

Red Signal not having lyrics on Spotify is so fucking funny to me

[saym0-0]

that clip of ben meredith being asked to do the eldrich chant at the start of red signal and jonny yelling from the back 'you butchered it!' lives in my brain rent free

[cryptile]

Drumbot Julian and Jonny d'Bee (@jonny-b-meowborn ) are real.

Don't let the heavenly atmosphere fool you, we're about to fuck you up

Textless version since i have it

[blazeismyname]

There's a unsung hero of The Mechs Fandom I feel I must address. If you've searched up The Mechs or Mechs' lyrics, you'll have seen a video by TheVoidSings probably. We'll, THEY'VE DONE IT FOR EVERY SONG. They're super awesome and if you know about them, just share this around for the other mechs fans who don't!

Link to their playlist:

[jonny-b-meowborn]

in the ratatosked express. straight up "jorking it". and by "it", haha, well let's jusr say. My peanits

[bonzobotdrum]

So I decided to chuck some things through this website and got some cursed results

not Yumr Bonzo and Yog-satisthoth

[hellsite-proteins]

Love the concept and love your analyses! Protein request, if the length's alright:

Y'AI 'NG'NGAH, YOG-SOTHOTH H'EE-L'GEB F'AI THRODOG UAAAH. OGTHROD AI'F GEB'L-EE'H YOG-SOTHOTH 'NGAH'NG AI'Y ZHRO

ÏA, ÏA ÏA YOG-SOTHOTH

(if this is referencing other than red signal by the mechanisms and i'm simply too uncultured to recognize it, please lmk!)

letter sequence in this ask matching protein-coding amino acids:

YAINGNGAHYGSTHTHHEELGEFAITHRDGAAAHGTHRDAIFGELEEHYGSTHTHNGAHNGAIYHR

protein guy analysis:

i'm going to be honest, i had hope in this one. the pattern of these letters felt pretty different from english, and so i thought that with this short structure, we may still get something. of course, i was wrong, and this thing didn't even manage to fold into any secondary structure, and the entire molecule only contains 2 hydrogen bonds. there are so many histidines (18% of the protein, compared to the expected frequency of 3%), which probably contributed to how weird this looks. histidine is very neat and a great amino acid to have in an active site, but this is too much.

predicted protein structure:

cartoon representation

cartoon with side chains coloured by heteroatom

[mechs-track-tournament]

SEMIFINALS